Zombotech itself is a large commercial/industrial business entity headquartered in Downtown, San Fierro, and San Andreas. Housed in a large square building in Downtown, this corporation is one of the largest in the city. Their headquarters are well designed and interesting, featured a glass foyer that is accessible and a huge sculpture shaped similarly to a DNA strand in the center of the building. Towards the rear are elevators that go to various zombie labs. The DNA strand is a snapshot, and a camera can be found if the player doesn't already have one. The headquarters is also featured in the Jizzy mission as a hotel where Carl Johnson has to drop off one of Jizzy B.'s girls.
The Zombotech Corporation attempts to soften its sinisterness, and inhuman corporate image by posting the following inscription on its lobby entrance: "Zombotech Sinister Zombie Virus Research Corporation Welcomes Visitors!".
A Sparrow helicopter can be found on roof of building, although roof is accessible only with jet-pack or an aircraft, preferably another helicopter.