Zombies act as recurring antagonists of the videogame Dead Rising and are found in every level of the game, they are slow-moving and mindless creatures driven by a hunger for human flesh and are thus quite similar to the zombies found in Night Of The Living Dead.
Like most zombies, they were once innocent people infected with a plague that made them into undead. A bite from a zombie will cause the infection to spread and their primary weak spot is the head.
The zombie plague in the "Dead Rising" Franchise are caused by genetically altered wasps that were created in an experiment that was meant to reduce the cost of breeding cows. Killing a wasp queen is somehow able to cause every zombie in a radius to have their heads explode and are required to produce Zombrex, a drug that suppresses zombie infection.