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Yumie is the violent split personality of Yumiko Takagi, a nun who works for the Iscariot section of Vatican. She usually partners up with Heinkel Wolfe.
Yumiko is a fearful, timid, quiet nun with Multiple Personality Disorder who is a pacifist, and is easily frightened and pusillanimous. However, when her glasses come off, her alter-ego, Yumie, is unleashed. Yumie is very reproachful, censorious, impulsive, and violent, showing no fear of anything and preferring to negotiate using the sharp end of her katana. She seems to genuinely enjoy killing people, having almost superhuman strength: she is adept enough to kill her victim from outside the room, and is capable of smashing heads into walls with her bare hands. Yumiko has often commented how hard it is for her to "get Yumie to sleep" after she has been provoked into action. Her raw strength, fearlessness, and fearsome katana skills make her the ideal partner to Heinkel, who is imperturbable, cool-headed, and analytical. Both Yumiko and Yumie are devout to their religion; however, Yumie is loyal to her church to the point of fanaticism, and is glad to slice down anyone she sees as a "heathen".
Yumiko always dresses in a standard Catholic nun's uniform, which consists of black robes, a nun's hooded cowl, a white scarf, and white gloves. She has long black hair, although little of it is visible beneath the cowl, and wears glasses. When her glasses come off- whether she removes them or they are forcibly knocked off - Yumie "wakes up". Yumie prefers to remove the nun's cowl, keeping the scarf around her neck and letting her hair flow free. Yumie also has slightly narrower eyes and usually can be seen with a maniacal grin. She also carries her katana, holding the sheath in one hand and the blade in the other when in use. She wields the sword in either hand. Yumiko Takagi is noted to be the only Hellsing character stated to be of Japanese ethnicity.
In Hellsing chapter 74 Relics, she attacks Walter, enraged after seeing him desecrating Father Anderson's remains, and at how coldly he betrayed Hellsing. Although moving extremely swiftly, she is outmatched and cut into pieces by Walter's wires. Heinkel is hysterical and overwrought, so she aims her guns at Walter, only to be shot and wounded by the Captain. Yumie makes a full appearance in OVA V.