The Vampires are the race of undead bloodsuckers and the supporting antagonists in Van Helsing. Their leader is the first of their kind, Count Dracula
Since after Dracula became what he is now as the world's first vampire, he began amassing an army of vampires and one by one they begin to grow until they trap all of the Romanian land of Transylvania in a nightmarish state of fear.
Van Helsing came to Transylvania and slain one of Dracula's vampire servant.
Soon in the film he is seen with Anna Valerious's Werewolf brother, Velkan Valerious, to power a machine at Frankenstien's Castle to bring to life his Vampire Children. His plan then fails when Van Helsing begins to shoot and destroy the Vampire Children that come to life while the machine is powered, and later speaks to Van Helsing about that he had been alive for hundreds of years, along with the fact that he had supposably known Van Helsing many years ago, before Van Helsing and Anna escape.
Dracula is then seen with a captured Anna Valerious at a ball in his Slumber Palace, dancing with her and telling her that he needed a new bride, and he nearly bites her to turn her into a Vampire, when Van Helsing comes and saves her life, before being chased by Dracula's Vampire people in their masqerade costumes during their escape. All the vampires in the palace were destroyed by a bomb-like device that emits intense rays of light and killed.
In the final confrontation in Dracula's castle, Dracula transforms into a fearsome bat creature when Van Helsing transforms into a Werewolf after being bitten by one-Anna's Brother, Velkan.
They battled and Dracula tells Van Helsing that he was the one who killed him years ago.
Eventually, after this information was told, Van Helsing kills Dracula once and for all, ending the terrifying reign of the Vampires and lifting Valerious's curse.