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Carmella Unuscione was a member of the second lineup of Acolytes loyal to Magneto under his second-in-command, Exodus. She was one of the more loyal members, exhibiting at times great passion and determination for Magneto's cause. Unuscione and her teammates battled the X-Men, Excalibur, and other super humans on numerous occasions.
Carmella was one of the Acolytes responsible for bringing the young mutant, Simon Hall (Neophyte) to Avalon, after finding him distraught in an abandoned church in Switzerland.
When Avalon fell during the battle between Holocaust and Exodus. Unuscione and her teammates Scanner, Joanna Cargill, and the Kleinstocks were trapped in an escape pod with the X-Man Cyclops. Unuscione used her power to protect them from burning up on reentry into Earth's atmosphere. Unuscione, Cyclops, and her teammates landed in the Australian outback, and in exchange for Cyclops leading them to safety, Unuscione and her teammates agreed to turn themselves into government custody. They later escaped, however, and returned to Magneto, who was now in Genosha. It was there that she was last seen, still loyal to Magneto.
Unuscione was one of the few mutant who retained their powers following M-Day. She returned to action as a member of the newest incarnation of the Acolytes as they attacked the X-Mansion. The group attempted to retrieve Destiny's Diaries under Mister Sinister's orders, but were tricked into stealing fake duplicates. During a conflict against the New X-Men, Kitty Pryde, and her former teammate Colossus, Unuscione battled Armor.