Twitch is the leader of the Outlaw Cats, and the secondary antagonist in An American Tail: The Mystery of the Night Monster. He is voiced by John Mariano. He is Madame Mousey's man servant. He has a very short temper, and he gets easliy abused by Mousey throughout the song "Creature de la Nuit".
Twitch despises Mousey and teased her about her problems with the other dogs. When they came back after a failed attempt to get rid of Nellie and Fievel, Twitch tries to get the cats to turn on Mousey because he believed they were better off without her and since they had Mousey's sewer maps, they had a way to get past the mice gate that protects them from the cats. At the near end of the film, Twitch and his minons attack Fievel, Nellie, Reed, and Tanya with Mousey's monster machine. However it gets destroyed but Twitch survived and he attacks Reed and Nellie, but Fievel saved them and he tries to catch Fievel. But he gets defeated when Fievel tricks him by activating the printing newspaper machine, and he got rapped up in a newspaper. It is unknown what happened to him after that. He could be sold to an owner, escaped being tied up, or he died from suffocation.
- He could be one of the followers of Warren T. in the first movie, which explains why he lived in the sewers with the other cats.
- The chase scene with Twitch and Fievel, mirrors Tom and Jerry.
- Papa reads in the newspaper that the Outlaw Cats had run away, so it is possible Twitch was one of them.