The Titanoboa came in the present through an Anomaly and kill many people. He confronts Evan Cross and Leo John, but they escape from him. Finally, with the help of Detective Harlow, Evan and Mac Rendell manage to send him back to his time through the Anomaly.
- The Titanoboa from Primeval: New World uses his hearing for hunting. However, in real life, a snake can't hear due to its lack of ears.
- He is far longer than real Titanoboa.