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Takofanes can also be faced by heroes every Halloween, which is the only time of the year that the dreaded Lich can actually be temporarily defeated - since during the Blood Moon he is generally unable to be harmed: heroes fighting only his zombie minions and avatars.
Due to the "Blood Moon" occuring once every month and the high-level drops and achievements available Takofanes is one of the more well-known and popular Cosmic villains in the game (next to Grond) and despite him being an extremely dark and twisted villain in-game fans have joked slightly on his name due to it often being shortened in chat to "Tako" (which resembles the food "Taco" ).