Swayzak was the main antagonist in the Toonami Total Immersion Event "Trapped in Hyperspace". When TOM and SARA headed into hyperspace, SARA's system crashed. The system is taken over by Swayzak, an evil virus. He managed to take control of the ship and although he's been stopped many times, he manages to keep on coming back, since he is a virus. He is seen in the 4 of the 5 part mini episodes of Trapped in Hyperspace, mainly taunting TOM on how he will never be stopped. He is also called the devil virus since he appears red with horns, but with physical features of a robot. Of course, though, TOM didn't give up that easily, and he kept transmitting into the Absolution's system to attempt to eject Swayzak from there. TOM finally succeeded, and with Swayzak gone, SARA returned alive and well.
Swayzak also made a cameo appearance in SARA's game review of Rez. The voice actor of Swayzak is unknown, and will likely remain that way, according to Toonami co-creator Jason DeMarco.