Spyder is a Marvel comics super-villain who first appeared in New Mutants Vol.1 66.

Spyder is the alien head of the Webb, an intergalactic trading organisation that he claims is a textile manufacturing company. His principal interest, however, is the gaining of wealth through unscrupulous business practices. Spyder justifies his amoral actions as reasonable business practices, claims to adhere to contracts no matter how unfair others may judge them, and regards the slaves he acquires through his dealings as no more than merchandise.