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Spider Slayers

Spencer Smythe and his Spider-Slayers.

The Spider-Slayers are a series of killer robots from Marvel Comics that were created specifically to hunt and kill Spider-Man. The original Spider-Slayers were made by robotics expert and scientist Spencer Smythe, who was funded by J. Jonah Jameson. Smythe's first few models were clunky, yet dangerous humanoid robots that had verious functions designed to stop Spider-Man's powers. These were all easily defeated by the resourceful web-slinger, and Smythe continued to make newer and more improved versions, these having an insectoid-type shape to keep up with Spider-Man.

Alistair's Spider Slayer

One of Alistair's upgraded Slayers.

After Spencer died from radiation poisoning, his son Alistair took the reigns and sought revenge on Spider-Man. His versions of the Spider-Slayers were powerful, terrifying monster-robots that gave Spidey a real challenge.

Spider-Slayers

Animated, Combined Spider Slayers

Spider Slayer

The Spider-Slayers also appeared in Spider-Man: The Animated Series and came in three versions, all designed to look like various arachnids. They could combine. They appear as the main antagonists in the second and third episodes.

          Spider-Man Villains

Comics
Absorbing Man | Agony | A.I.M. | Alistair Smythe | Annihilus | Answer | Arcade | Awesome Android | Basilisk | Beetle | Beyonder | Black Cat | Blackie Drago | Blastaar | Blob | Bombshell | Boomerang | Brothers Grimm | Burglar | Bullseye | Bushwacker | Calypso | Carnage | Carrion | Chameleon | Chance | Circus of Crime | Constrictor | Crime Master | Crossbones | Dark Avengers | Deadpool | Demogoblin | Diablo | Doctor Doom | Doctor Faustus | Doctor Octopus | Doppleganger | Dormammu | Eddie Brock | Electro | Enforcers | Equinox | Firelord | Frightful Four | Ghost | Gog | Goliath | Graviton | Green Goblin | Green Goblin II | Grey Goblin | Grizzly | Hammerhead | Hand | Hazmat | High Evolutionary | Hitman | Hobgoblin | Human Fly | HYDRA | Hydro-Man | Jackal | Jack O' Lantern | Jigsaw | J. Jonah Jameson | Johnny Ohm | Jonas Harrow | Juggernaut | Justin Hammer | Kaine | Kangaroo | Killer Shrike | Kingpin | Knull | Kraven the Hunter | Lady Deathstrike | Lightmaster | Living Brain | Lizard | Loki | Madame Viper | Magneto | Mandarin | Man-Spider | Man-Wolf | Menace | Mephisto | Mesmero | Mister Fear | Mister Hyde | Mister Negative | Mojo | Molten Man | Morbius | Morlun | Moses Magnum | Mysterio | Nekra | Nightmare | Niles Van Roekel | Nitro | Onslaught | Overdrive | Owl | Phil Urich| Psycho-Man | Puma | Punisher | Ramrod | Red Ghost | Red Skull | Rhino | Rhino II | Richard Fisk | Ringer | Riot | The Rose | Roxxon | Sabretooth | Sandman | Sauron | Scarecrow | Scorcher | Scorpion | Scream | Sebastian Shaw | Secret Empire | Sentinels | Shocker | Shriek | Silver Sable | Sinister Six | Skrulls | Speed Demon | Spidercide | Spider-Slayers | Spot | Stilt-Man | Street | Super-Apes | Swarm | Symbiotes | Tarantula | Taskmaster | Terminus | Thunderball | Thunderbolts | Tinkerer | Titania | Titanium Man | Tombstone | Trapster | Tyrannus | Venom | Vermin | Vulture | Walrus | White Rabbit | Will-O'-The-Wisp | Wizard | Worthy | Zodiac

Movies
Spider-Man: Norman Osborn/Green Goblin | Dennis Carradine | J. Jonah Jameson
Spider-Man 2: Otto Octavius/Doctor Octopus | Harry Osborn/New Goblin | J. Jonah Jameson
Spider-Man 3: Eddie Brock/Venom | Flint Marko/Sandman | Harry Osborn/New Goblin | J. Jonah Jameson
The Amazing Spider-Man: Curt Connors/Lizard | Gustav Fiers | Cash Register Thief | Norman Osborn
The Amazing Spider-Man 2: Max Dillon/Electro | Harry Osborn/Green Goblin | Donald Menken | Aleksei Sytsevich/Rhino | Alistair Smythe | Ashley Kafka | Felicity Jones
Spider-Man: Homecoming: Adrian Toomes/Vulture | Bestman Salvage (Phineas Mason/Tinkerer, Jackson Brice/Shocker #1, Herman Schultz/Shocker #2 & Randy Vale) | Mac Gargan | Aaron Davis
Venom: Eddie Brock/Venom | Carlton Drake/Riot | Roland Treece | Cletus Kasady