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|“||Looks like the freak wants to play!||„|
|~ A Skulls Gang member|
The Skulls Gang are a gang of street thugs in the 2002 Spider-Man video game based on the movie created by Sam Raimi. Their leader is Uncle Ben's Killer nicknamed in the game as Spike.
Spider-Man investigates the rooftops of New York to learn the whereabouts of his uncle's killer from one of the thugs. He learns from one thug that their leader is at an abandoned warehouse. Spider-Man enters the warehouse and defeats all thugs and eventually confronts Uncle Ben's Killer. After the killer's death, the Skulls gang dissolves.