Shriek is a criminally insane supervillainess and an enemy of Spider-Man .
Frances Louise Barrison spent her childhood being abused by her mother for being overweight. She was driven to drug use and developed a fixation of becoming a mother herself. Barrison eventually became a drug dealer, leading her into several situations that were harmful to her sanity, including being shot in the head by a police officer. She eventually ended up in Cloak's dark dimension, which caused her to develop the ability to manipulate sound.
Shriek was incarcerated in the criminal mental hospital, Ravencroft, when Carnage caused a mass breakout. Upon seeing their mutual psychopathic sadism, the two "fell in love" and teamed up, and went on a killing spree. They also teamed up with three other homicidal villains, Demogoblin, Carrion, and Doppleganger, forming a "family". However, they were stopped by Spider-Man, Venom, and Black Cat. Shriek has since tried escaping Ravencroft several times, each time battling Spider-Man.