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| "Sam" may be referring to two or more different villains. If you're uncertain which one you're looking for, just flip a coin.|
If you came here from a link, please go back and make the right link for one of the villains listed below.
- Hon Sam - A character from The Infernal Affairs Trilogy
- Sam (Mafia: The City of Lost Heaven) - A character from Mafia: The City of Lost Heaven
- Sam Farren - A character from Scooby Doo
- Sam Crenshaw - A character from Scooby Doo
- Yosemite Sam - A character from Looney Tunes
- Sergeant Sam Roderick - A character from Spongebob Squarepants
- Dr. Sam Isaacs - A character from the Resident Evil film series
- Sam (Trick 'r Treat) - A character from Trick 'r Treat