Rita Garrison is a one-shot villainess from Murder, She Wrote. She appeared in Season Seven's second episode, "Deadly Misunderstanding."
She was played by the late Janet Margolin (in her final role).
Rita Garrison is the wife of creative writing professor Drew Garrison, but she was also having an illicit affair with Ralph Maddox, who was married to Jessica Fletcher's inter, Melissa. Late one night, Rita drove to Ralph's home with intentions of furthering their relationship, but she found out that Ralph had consorted in a one-night stand with another woman. In a furious rage, Rita killed Ralph with a pair of scissors. Rita referred to Ralph as a "real man" during her villainous revelation, but later stated that she felt "unclean" after realizing what type of man he really was. Rita was arrested for Ralph's murder.