Prior to its corruption by red lyrium, this creature was a high dragon of unknown origin. She makes her first formal appearance with Corypheus at the village of Haven during his assault and attempt to obtain the Anchor from the Herald of Andraste. It is initially assumed that the dragon is an archdemon, and that it brings the possibility of a new Blight, spreading fear across Thedas.
The dragon is also summoned by Livius Erimond to aid him during the Inquisition's siege of Adamant Fortress. When Warden-Commander Clarel turns against Erimond and has him at her mercy, the dragon swoops down and mauls her before tossing her aside. Before the beast can attack the Inquisitor, Hawke, their Warden ally (either Stroud, Alistair or Loghain), and their party, however, Clarel casts one last spell with her dying breath, striking the dragon's underbelly, causing it to collapse and weaken the walkway under their feet. The dragon then flees the area while the Inquisitor disappears into the Fade.
During the Inquisition's assault on the Temple of Mythal, Corypheus summons his dragon again to attack the Inquisitor and Morrigan, but they manage to evade her and escape into the magically warded structures of the temple.
If either the Inquisitor or Morrigan drinks from the Well of Sorrows, they learn that Corypheus' dragon is not a true archdemon, but merely a facsimile of one made by corrupting an ordinary high dragon with red lyrium in which the magister invested his power. If the dragon is killed, then Corypheus' ability to leap into other bodies would be removed.
During the final confrontation, the dragon attempts to pounce at the Inquisitor, only to be tackled out of the way by another dragon (either the Guardian of Mythal or a transformed Morrigan). The two dragons engage in an aerial battle before Corypheus' dragon manages to defeat its opponent. The Inquisitor then finishes the weakened dragon off, before taking on her master.
- The Red Lyrium Dragon can be compared to Nagini as both are female reptiles who also act as both pets and sources of their masters immortality (Nagini as one of Voldemort's Horcruxes and Red Lyrium Dragon as the source of Corypheus' ability to leap into other bodies) and both of their deaths cause the downfall of their masters.