Psycho is the quinary antagonist of Who Framed Roger Rabbit. He is the most insane weasel in the gang.
He wears an unbuckled straitjacket, has blue eyes with yellow and white swirls and his weapon of choice is a straight razor.
He apparently gets excited by the concept of killing, as he is heard gleefully laughing when Judge Doom kills the toon shoe in the bucket of dip; he is nearly drooling in anticipation as Smarty attempts to drive into Benny the cab, and he takes it upon himself to shoot the dip at Roger and Jessica.
Psycho is the last weasel to die, not by losing control of his laughter, but by losing his footing and dropping on the giant rotating brush of the Dip Machine.
He only has two lines in the film; he first speaks as he prepares to shoot dip at Roger and Jessica, when he says "Time to kill the rabbit" and when he waves "Bye-bye" after he dies.
On a few occasions, it is implied that he enjoys pretending his straitjacket is buckled by hugging himself tightly, namely when he exits the Toon Patrol's car in his first appearance, and while laughing after Eddie stuffs a bar of soap into Smarty's mouth. He remained a threat after his death; as his soul rose out of the warehouse, he turned the pressurized dip spray back at Roger and Jessica.