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ProfNibbles

Professor Nibbles is a one-shot villain in Disney's Phineas and Ferb. He serves as the villain of a fictional show named Katt Karr (created by Phineas Flynn and Ferb Fletcher). He wears a mouse costume and only appears in the episode Ferb TV.

Role

According to the episode, his nemesis (played by Danville Mayor Roger Doofenshmirtz, the younger brother of Dr. Heinz Doofenshmirtz) and a sentient car resembling a cat called Katt Karr are hunting down Professor Nibbles for some unknown crime he commited.

During the chase as both Roger and Katt Karr catch up to him driving in his motorcycle, Nibbles takes out a ball of yarn and cackles evilly as he throws it out, knowing that cats can't resist playing a ball of yarn. This distracted Katt Karr to chase after the ball of yarn to let Nibbles speed off more, much to Roger's anger and frustration.

However, in the end, Roger and Katt Karr inexplicably manage to stop Nibbles, who ends up being restrained by Roger while Katt Karr coughs up a huge hairball from unknown causes, much to both Roger and Nibbles' horror. It is implied that Nibbles is sent away to prison for his crime.

           Phineas and Ferb Villains

Doofenshmirtz Evil Incorporated
Heinz Doofenshmirtz | Vanessa Doofenshmirtz | Norm | Gelatin Monster | Doofenshmirtz's Mecha | Rodrigo | Mindless Repulsive Pharmacists

L.O.V.E.M.U.F.F.I.N.
Aloyse Von Roddenstein | Dr. Bloodpudding | Dr. Diminutive | Orville Von Roddenstein | Professor Bannister | Bannister's Thugs | Me-Positive & Me-Negative | Dr. Killbot | Warehouse Goons

Doofenshmirtz Family (2nd Dimension)
Heinz Doofenshmirtz (2nd Dimension) | Charlene Doofenshmirtz (2nd Dimension) | Vanessa Doofenshmirtz (2nd Dimension) | Norm-Bots | Goozim | Animal-Borgs (Perry the Platyborg, Peter the Pandaborg & Pinky the Chihuahuaborg) | Tony Marzulo

Other Evil Scientists
Professor Destructicon | Dr. Gevaarlijk | Mitch | The Regurgitator | Esmeralda Poofenplotz | Khaka Peü Peü | Evil Carl (Evil Flynn-Fletcher Robots) | Mittington Random (The Klimpalooners) | Professor Mystery | Professor Parenthesis (Mecha-Fleas)

Time Shift
Jekyll Doofenshmirtz | Doofengung | Doofus Khan | Doofenshmirtz (1914) | Corn Colossus of Juatchadoon | Norm (1914) | Professor Von Doofenshmirtz | Pneumatic Pnorman | Darthenshmirtz | Darth Ferb | Candace's C.O. | Norm-3PO | Stormtrooper Candace | Stormtrooper Baljeet | Stormtrooper Buford

Fictional Characters
Control Freak | Smile Away Reformatory School Sergeant | Giant Buford | Malifishmertz | Meatlings | Lawn Gnorme | Keeper of the Bridge of Comprehension | Candace's Id | Worthington Dubois | Professor Nibbles | Der Kinderlumper

Misc.
Brobots | Suzy Johnson | Dennis the Rabbit | Busting Candace | Potato Gremlins | Liam McCracken | Morg | Peggy McGee