~ Pipe Hybrid

The Pipe Hybrid is the first enemy encountered in System Shock 2, and one of the least threatening. Hybrids are humans who have been infected by the parasitic Annelids, and mutated into monsters in service of the Many. They make up the majority of enemy resistance on MedSci Deck, and typically appear on every other level, albeit in significantly reduced numbers later into the game. They are fairly easy to dispatch, and are limited to melee attacks.

Attributes: Low Hit Points, low damage, low attack speed, medium movement speed

Weaknesses: Anti-Personnel Bullets, Anti-Personnel Shotgun Shells, incendiary damage,Psionic Hypnogenesis, Stasis Field Generator, Imposed Neural Restructuring

Common Loot: Hybrid Organ, Soda, Chips, Juice, Nanites, Bullets and Shells


Hybrids are generally slow-moving, and are limited to a melee attack, courtesy of the lead pipes they carry. Although their lack of a ranged attack might suggest that taking them out from a distance is preferable, their low attack speed makes them easy to kill even in close combat. Your best bet is to circle-strafe around them and attack using your Wrench or another melee weapon; chances are you'll take little to no damage in the process.

  • If you have Research skill, be sure to investigate the first Hybrid Organ you find, it will give you a damage bonus against all Hybrids, not just those wielding Pipes.