The Pickloids are an alien race that are the main villains of The Powerpuff Girls: Relish Rampage.
The Pickloids have invaded Townsville and want to transform the humans into Pickloids. After one of their karate generals was killed, the Pickloid Captain met the Mayor of Townsville and planned to brine him inside the mothership. Now that the Pickloids have been defeated by the Powerpuff Girls, they decided to settle a colony at Jargon. However, they were eaten by a Jargonian Ice Toad.
- The Pickloids are counterparts to another Powerpuff alien race, the Broccoloids.