Nukesaku is a minor villain from the third arc of JoJo's Bizarre Adventure. One of Dio Brando's minions, he appears after Dio's other henchmen, Terence T. D'Arby, Kenny G. and Vanilla Ice, have been defeated by the heroes, though he's actually satisfied by their defeat, because they had mocked him before.
When Jotaro, Joseph and Kakyoin are rushing after Dio on his mansion, a woman appears begging for help. While the heroes calm her down saying they're friends, Jotaro punches her, revealing that it was actually Nukesaku, who grew a woman's face on his back. When Nukesaku asks how they found out, Kakyoin points that he didn't twist his hands accordingly to keep the facade. After being mocked by the heroes, he attempts to bite Jotaro, only to be punched out again and forced to take the heroes to Dio's room. Once there, they demand him to open Dio's coffin, but as he removes the lid, he suddenly appears inside the coffin, with his body sliced to pieces, as a result of Dio using his stand The World.