Nuke (real name: Bane Simpson) is a villain in the Amalgam Comics. Nuke's an enemy of Black Bat, Moonwing, and a few other heroes. He's the combination of the DC villain; Bane, and the Marvel villain; Nuke. He's also a member of the Amalgam version of HYDRA.
Much like Bane, Nuke is a test subject of the super-drug known as Venom. Without it Nuke has average strength, but with the Venom, Nuke strength and speed are increased to superhuman-levels.