Ms. Tweezer was the main antagonist of the Chalkzone episode, Protable Portal. She despises imagination and wants people to think everything fictional is bad. She trapped Rudy in her trailer and tortured him with contraptions and a quiz with distrubing results. Snap however, came to the rescue and stopped Tweezer and exposed Chalk Zone to her which drove her insane. Mrs. Tweaser's "De-Magination Session" involving the viola and the horn is a method of torture and child abuse, which is illegal in all 50 of the United States.
- After that episode, she was never seen or mentioned again.
- She is similar to Lamar Bone from Doug.