Ethel Rogers is one of ten people summoned to Indian Island by Lawrence Wargrave in Agatha Christie's novel 'And Then There Were None,' who have committed murder in a way that the law cannot prove or punish them for. She is the cook and Mr. Rogers' wife. She is described as a pale-faced, ghostlike woman with shifty light eyes, who is scared easily. Despite her respectability and efficiency, she helped her domineering husband, Thomas, kill their elderly employer Jennifer Brady by withholding her medicine, so they could inherit her money. Since she was mostly manipulated by her husband in the crime, Wargrave decides she is one of the least guilty of the ten guests, and by his planned order of death, she is in the first group to die, being spared the mental strain reserved for the later victims. After she faints hearing her crime repeated to her, she is carried up to bed and given a sedative by Dr. Armstrong. Later in the night, however, Wargrave enters her room and poisons her, letting her die in her sleep, corresponding with the 'Ten Little Indians' rhyme, "One overslept himself and then there were eight."

Wargrave later confesses that she and Rogers were the first victims he discovered, learning of their crime from a doctor who treated their employer and guessed their motive, but was unable to prove it.