I am the most powerful Pokémon of all; stronger even than Mew.
~ Mewtwo

Quiet, human. From now on, I'm the one who makes the rules.
~ Mewtwo, while possessing Nurse Joy, to a trainer.

You humans are a dangerous species. You brought me into your world with no purpose but to be your slave...but now I have my own storm will create my own destroying yours....
~ Mewtwo revealing his plan and his misanthropic personality.

Mewtwo is the main antagonist of Pokémon: The First Movie and an anti-hero in Mewtwo Returns. His goal was to exterminate all humans and their Pokémon, and repopulate the world with clones of Pokémon but later would reform and help the heroes.

In the Japanese dubbed version, he was voiced by Shōtarō Morikubo as a child, and by Masachika Ichimura as an adult. In the English dubbed version, he was voiced by Philip Bartlett in The First Movie, and by Dan Green in Mewtwo Returns.


We dreamed of creating the world's strongest Pokémon...and we succeeded.
~ Dr. Fuji's famous last words.

According to "The Origin of Mewtwo", a piece of bonus footage included with the Mewtwo Returns DVD which expands his back-story, he interacted with several clones of a Charmander, Squirtle, Bulbasaur, as well as a clone of Amber, the daughter of Dr. Fuji. He was eventually distraught over his friends, especially Amber's premature death, which also resulted in the scientists injecting him with a serum that removed his memory of her, which is strongly implied to have impacted his behavior in the film.

However, Mewtwo was angered by the team as he heard that he was to be controlled by them, and that he may not be part of God's creation, and in his fury, destroyed the lab where he was created, and killed all the scientists with his intense psychic powers. He then allied himself with Giovanni under the promise of learning to control his powers, although he later rebelled from Giovanni after learning that Giovanni's claim of partnership had been a lie, and he had already been sickened by Team Rocket's actions towards Pokémon. Believing humans as oppressors of Pokémon, he vowed to exterminate humans and all Pokémon that sided with them, believing it to be his "purpose". He also wishes to exterminate his predecessor Mew, as he believed he was vastly superior to his genetic counterpart. He eventually saw the errors of his ways shortly after Ash Ketchum sacrificed himself to stop their fighting and all the touched Pokémon use their tears to revive Ash. Departing with Mew and the other Pokémon clones, Mewtwo removed their memories to avoid being tracked down.

Mewtwo serves as an anti-hero in Mewtwo Returns. He was hiding in Kena Mountain with the other clones. He saved a bus with passengers, but he claimed to feel no compassion for the humans. When Giovanni managed to find both Mewtwo and the other clones, he decides to help all of the Pokémon. He was proven to be a great ally for Ash and his friends. Later, when Ash told him he will tell Professor Oak about him and the source, Mewtwo wanted to erase their memories again. But Meowth managed to convinced Mewtwo that they should keep their memories. Mewtwo agreed to let them remember him and the others but he only erased the memory of the people who wanted to destroy them. After erasing the memory of Giovanni, who winds up leading his army out of the falls, Mewtwo takes leave of the gang, this time for good, on the condition that his spirit crosses time and space to theirs.


I see now that the circumstances of one's birth are irrelevant. It is what you do with the gift of life that determines who you are.
~ Mewtwo, upon learning the true meaning of life.

Mewtwo's uniqueness largely stems from his psychic abilities. However, his personality is one of the defining points in the Pokémon series. Mewtwo's personality is initially complex involving existentialist anxiety, and contemplating the meaning of existence. His temperament is very withdrawn, introverted, and contemplative, consisting of hate and anger towards humans and his creators.

Having been brought into existence through artificial means, Mewtwo quickly turned on his creators when he learned that they intended to experiment on him further. Feeling betrayed by the very humans that had created him, he decided to forge his own path. The recurring theme in the films is Mewtwo harboring jealousy towards Mew because he is a copy or derivative, whereas Mew is the original.

In the first film, the path that Mewtwo has taken makes him into a rather cruel, immoral, nefarious, exploitative, and calculating character. He frequently exhibits cruelty, and at several intervals, goes so far as to attempt to (or forthrightly) kill those who oppose him. He also shows no qualms about forcing Nurse Joy to serve as his puppet, and then casting her aside once she was of no further use to him. This makes Mewtwo easily one of the most manipulative and malicious characters in the series and the main antagonist in Pokémon The First Movie, prior to his change of heart at the end of the first films.

However, in Mewtwo Returns, Mewtwo is much more kind, lenient, and sympathetic, so he only wants to protect the other clones that he created. He even protected some humans that were on a bus getting thrown around by strong winds. Therefore, Mewtwo is a hero in his second film, and a victim. When Giovanni comes on the mountain, Mewtwo is willing to sacrifice himself to save the other clones, as well as Ash's Pikachu and Team Rocket's Meowth. Also, he constantly wants to avoid fighting, which is the exact opposite of the way he was in the first film.

So, it can be said that Mewtwo (upon Ash's sacrifice in Mewtwo Strikes Back) has become a hero instead of a villain. He continues to live in Johto and, as said by himself, "in shadows".

Powers and Abilities

I may have been cloned from your DNA, but now I will prove that Mewtwo is better than the original. Superior to Mew! This world is too small for two of us!
~ Mewtwo to Mew.

Mewtwo is a psychic Pokémon, endowed with immense mental powers, including telekinesis, telepathy, the power to fly or create rays of energy powerful enough to stand up to those of Mew.

Mewtwo has the ability to telekinetically create a massive hurricane and is constantly protected from harm inside a reflective sphere of psychic energy. In the English dub, it is claimed that the hurricane was powerful enough to destroy the planet, as well as Mewtwo being able to block a Pokémon's "special abilities." Mewtwo can also "communicate" with humans via telepathy, and was also capable of instant regeneration, allowing it to survive what would normally be fatal blows. This was especially evident when a computer, deducing Mewtwo as a threat shortly after bursting out of its containment field, shot Mewtwo with a laser that was potent enough to temporarily kill Mewtwo, only to regenerate from its wound and revive itself, as well as it regenerating from a flamethrower blast. According to the dub of Mewtwo Returns, its psychic abilities were ineffective against automated machines.


  • In the original Japanese release of Mewtwo Strikes Back, Mewtwo is a very different character. He comes of as more sympathetic, with no intention to harm humans. He instead does the things he does in an effort to prove his own worth and believed superiority to the world.
  • Even though Giovanni proved to be the bigger threat, Mewtwo was the main antagonist because he was the immediate threat that Ash and Pikachu had to face.


           Pokémon Villains

Team Rocket
Giovanni | Proton | Petrel | Ariana | Archer
Anime only: Jessie | James | Meowth | Matori | Dr. Zager | Butch | Cassidy | Dr. Namba | Madame Boss | Domino | Tyson | Iron-Masked Marauder | Pierce
Manga only: Lt. Surge | Sabrina | Koga | Will | Karen | Carl | Sham | Carr | Sird | Orm

Team Aqua
Archie | Matt | Shelly
Manga only: Amber

Team Magma
Maxie | Tabitha | Courtney
Manga only: Blaise

Team Galactic
Cyrus | Cyrus (Pokemon Anime) | Mars | Jupiter | Saturn | Charon
Manga only: Sird

Team Plasma
N | Colress | Shadow Triad
Seven Sages: Ghetsis | Zinzolin | Rood | Gorm

Team Flare
Lysandre | Malva | Aliana | Bryony | Celosia | Mable | Xerosic

Team Skull
Guzma | Plumeria | Gladion

Aether Foundation
Lusamine | Faba

Greevil | Evice | Ein | Lady Venus | Nascour | Miror B. | Dakim | Lovrina | Snattle | Gorigan | Ardos | Eldes | Hexagon Brothers

Manga Villains
Lorelei | Bruno | Agatha | Lance | Mask of Ice | Carl | Carr

Other People
Silver | Lawrence III | Annie | Oakley | Phantom the Pirate | Dr. Yung | Hunter J | Baron Alberto | Zero | Grings Kodai | Marcus | Damon | Damian | Mayor of Trovitopolis | Ninja Riot | Marilyn Flame | Argus Steel | AZ | Alva | Roger Clifford | Miyamoto | Cross

Mewtwo (Anime) | Mimikyu | Deoxys | Yveltal | Entei | Unown | Darkrai | Giratina | Arceus | Zekrom | Reshiram | Kyurem | Red Genesect | Genesect Army | Munna | Malamar | Spiritomb | False Groudon | Shadow Lugia | Giant Tentacruel | Mirage Mewtwo | Evil Togepi | Hoopa Unbound | Nihilego | Necrozma | Ultra Beast

Dusknoir | Snover | Rayquaza | Darkrai (2011) | Primal Dialga | MechaMew2