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Many are the good men who can resist murder, theft, and cruelty. But a touch of greed? A bit of laziness? These are the seeds of the ruination that can bring down the best of men!
~ Mephisto

Mephisto, sometimes using the name Mephistopheles or even Satan (among many others) is a powerful demonic super-villain from Marvel comics and is one of several such demons that feed off humanity's belief in The Devil so as to masquerade as Satan himself. In reality, however, Mephisto's origin seems to lie with the primordial Elder-Gods that ruled earth before being banished by Atum the God-Eater, the exact nature of this origin varies with story to story but tends to vary between the old gods becoming corrupt or the demons being formed by the already plentiful corruption found in the Elder-Gods.

At any rate Mephisto now rules over his own dark dimension, commonly called Hell but not related to the Biblical hell (though to the average human being it may as well be as it is equally as horrific), within this realm Mephisto rules supreme with only demons such as Blackheart (his own son) being capable of challenging him there.

Outside his realm, however, Mephisto becomes much more restrained, although still a virtually limitless sorcerer - he is aware of these limits and seeks ways to expand his influence throughout time/space but also, like many demons, enjoys causing misery and deception for no apparent reason other than malice. Mephisto's main enemies are the Silver Surfer, Fantastic Four, Dr. Strange, and Ghost-Rider, Ghost-Rider is especially prominent since he was formed due to a pact with Mephisto but dedicated himself to stopping the devil rather than working as his servant.

When May Parker died, Mephisto offered Spider-Man the chance to bring her back. In exchange, Peter had to surrender his love for Mary Jane.

Mephisto is also an enemy of Doctor Doom due to the demon having trapped and tormented the soul of his mother, Cynthia Von Doom (note that this is only relevant to the comic canon and may or may not apply to other versions of Dr. Doom).

Powers and Abilities

Mephisto, like The Devil's incarnation, is an extremely powerful being. He is immortal, and if he is destroyed, he will automatically reform himself in his domain.

Mephisto is endowed with a wide variety of demonic powers, even outside his realm: superhuman strength and resistance, metamorphosis, time control, illusions and mental manipulation.

In his Realm, Mephisto is all-powerful, able to change the structure of his world at will and able to rout even Galactus.

Live-Action Films

Main article: Mephisto (Live-Action Movie)

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          Ghost Rider Villains

Comics
Aqueduct | Arcade | Belasco | Blackheart | Blackout | Centurious | Crimson Mage | D'Kay | Darklove | Deathwatch | Doctor Doom | Enforcer | Flag-Smasher | Griffin | Hela | Hobgoblin | Jack O' Lantern | Kingpin | Lilith | Lord Pumpkin | Madcap | Manticore | Masters of Evil | Mephisto | Mister Hyde | Morbius | Nightmare | Night Terror | Null | Orb | Reverend Styge | Rigor Mortis | Scarecrow | Skin-Bender | Skinner | Spider X | Steel Wind | Succubus | Tatterdemalion | Troll | Varnae | Verminus Rex | Wallow | Zadkiel | Zodiac

Movies
Ghost Rider: Blackheart | Mephisto | The Hidden (Gressil, Wallow & Abigor)
Spirit of Vengeance: Mephisto | Blackout

Television
Eli Morrow | Lucy Bauer | Hellfire | Aida | Anton Ivanov

           Daredevil Villains

Comics
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Movies
Daredevil: Kingpin | Bullseye
Elektra: Kirigi | The Hand (Typhoid Mary & Tattoo)

Television
Season 1: Kingpin | James Wesley | Leland Owlsley | Vanessa Marianna | The Hand (Madame Gao & Nobu Yoshioka) | Bill Fisk
Season 2: Nobu Yoshioka | Punisher | The Hand (Madame Gao) | Elektra Natchios | Ray Schoonover | Kingpin
Season 3: Kingpin | Bullseye | Vanessa Marianna

           Fantastic Four Villains

Comics
Abomination | Abraxas | A.I.M. | Air-Walker | Annihilus | Apocalypse | Arcade | Arkon | Attuma | Awesome Android | Basilisk | Belasco | Beyonder | Blastaar | Brute | Bullseye | Collector | Constrictor | Count Nefaria | Destroyer | Devos the Devastator | Diablo | Doctor Doom | Doctor Faustus | Doctor Octopus | Doctor Sun | Elements of Doom | Enclave | Fin Fang Foom | Fixer | Frightful Four | Galactus | Giganto | Grandmaster | Graviton | High Evolutionary | Hydro-Man | Hyperstorm | Immortus | Impossible Man | Ironclad | Kang the Conqueror | Klaw | Kree | Kristoff Vernard | Living Laser | Lizard | Lucia von Bardas | Machinesmith | Magneto | Man-Ape | Mandrill | Master Pandemonium | Masters of Evil | Maximus | Medusa | Mephisto | Miracle Man | Molecule Man | Mole Man | Morgan Le Fay | Mysterio | Namor | Occulus | Onslaught | Overmind | Owl | Paibok | Psycho-Man | Puppet Master | Quicksilver | Red Ghost | Red Skull | Ronan the Accuser | Salem's Seven | Sandman | Sauron | Shocker | Skrulls | Stilt-Man | Super-Adaptoid | Super-Apes | Super-Skrull | Terminus | Thanos | Thunderball | Tiger Shark | Titania | Trapster | Ultron | Vermin | Whirlwind | Wizard

Movies
Fantastic Four (2005): Victor von Doom
Rise of the Silver Surfer: Galactus | Victor von Doom
Fantastic Four (2015): Victor von Doom

          Spider-Man Villains

Comics
Absorbing Man | Agony | A.I.M. | Alistair Smythe | Annihilus | Answer | Arcade | Awesome Android | Basilisk | Beetle | Beyonder | Black Cat | Blackie Drago | Blastaar | Blob | Bombshell | Boomerang | Brothers Grimm | Burglar | Bullseye | Bushwacker | Calypso | Carnage | Carrion | Chameleon | Chance | Circus of Crime | Constrictor | Crime Master | Crossbones | Dark Avengers | Deadpool | Demogoblin | Diablo | Doctor Doom | Doctor Faustus | Doctor Octopus | Doppleganger | Dormammu | Eddie Brock | Electro | Enforcers | Equinox | Firelord | Frightful Four | Ghost | Gog | Goliath | Graviton | Green Goblin | Green Goblin II | Grey Goblin | Grizzly | Hammerhead | Hand | Hazmat | High Evolutionary | Hitman | Hobgoblin | Human Fly | HYDRA | Hydro-Man | Jackal | Jack O' Lantern | Jigsaw | J. Jonah Jameson | Johnny Ohm | Jonas Harrow | Juggernaut | Justin Hammer | Kaine | Kangaroo | Killer Shrike | Kingpin | Knull | Kraven the Hunter | Lady Deathstrike | Lightmaster | Living Brain | Lizard | Loki | Madame Viper | Magneto | Mandarin | Man-Spider | Man-Wolf | Menace | Mephisto | Mesmero | Mister Fear | Mister Hyde | Mister Negative | Mojo | Molten Man | Morbius | Morlun | Moses Magnum | Mysterio | Nekra | Nightmare | Niles Van Roekel | Nitro | Onslaught | Overdrive | Owl | Phil Urich| Psycho-Man | Puma | Punisher | Ramrod | Red Ghost | Red Skull | Rhino | Rhino II | Richard Fisk | Ringer | Riot | The Rose | Roxxon | Sabretooth | Sandman | Sauron | Scarecrow | Scorcher | Scorpion | Scream | Sebastian Shaw | Secret Empire | Sentinels | Shocker | Shriek | Silver Sable | Sinister Six | Skrulls | Speed Demon | Spidercide | Spider-Slayers | Spot | Stilt-Man | Street | Super-Apes | Swarm | Symbiotes | Tarantula | Taskmaster | Terminus | Thunderball | Thunderbolts | Tinkerer | Titania | Titanium Man | Tombstone | Trapster | Tyrannus | Venom | Vermin | Vulture | Walrus | White Rabbit | Will-O'-The-Wisp | Wizard | Worthy | Zodiac

Movies
Spider-Man: Norman Osborn/Green Goblin | Dennis Carradine | J. Jonah Jameson
Spider-Man 2: Otto Octavius/Doctor Octopus | Harry Osborn/New Goblin | J. Jonah Jameson
Spider-Man 3: Eddie Brock/Venom | Flint Marko/Sandman | Harry Osborn/New Goblin | J. Jonah Jameson
The Amazing Spider-Man: Curt Connors/Lizard | Gustav Fiers | Cash Register Thief | Norman Osborn
The Amazing Spider-Man 2: Max Dillon/Electro | Harry Osborn/Green Goblin | Donald Menken | Aleksei Sytsevich/Rhino | Alistair Smythe | Ashley Kafka | Felicity Jones
Spider-Man: Homecoming: Adrian Toomes/Vulture | Bestman Salvage (Phineas Mason/Tinkerer, Jackson Brice/Shocker #1, Herman Schultz/Shocker #2 & Randy Vale) | Mac Gargan | Aaron Davis
Venom: Eddie Brock/Venom | Carlton Drake/Riot | Roland Treece | Cletus Kasady

           Marvel Avengers Alliance Villains

Abomination | Absorbing Man | A.I.M. | Apocalypse | Arcade | Arnim Zola | Avalanche | Baron Strucker | Baron Zemo II | Bastion | Batroc | Blackheart | Blob | Boomerang | Brotherhood | Bullseye | Carnage | Crimson Dynamo | Dark Avengers | Doctor Doom | Doctor Octopus | Dormammu | Dracula | Electro | Enchantress | Executioner | Fixer | Frost Giants | Grim Reaper | Hammerhead | Hand | Hela | Hellfire Club | High Evolutionary | HYDRA | Hydro-Man | Ironclad | Jack O' Lantern | Juggernaut | Kraven | Kurse | Lizard | M.O.D.O.K. | Madame Masque | Madame Viper | Magneto | Malekith | Man-Ape | Mandarin | Masters of Evil | Maximus | Mephisto | Mister Sinister | Morgan Le Fay | Morlun | Mysterio | Mystique | Nebula | Nitro | Norman Osborn | Red Skull | Ronan | Sabretooth | Sandman | Sauron | Sebastian Shaw | Selene | Shocker | Sinister Six | Surtur | Thanos | Thunderball | Titanium Man | Toad | U-Foes | Ultron | Umar | Vapor | Vector | Vulture | Whiplash | Wrecker | X-Ray | Ymir