Mel Gibson is the main antagonist of the Season 4 episode "North by North Quahog" in the Family Guy series.
Peter and Lois discovered that Mel Gibson intended on making a sequel to his already controversial film, The Passion of the Christ when they were in his private hotel suite. Feeling that the world had already had enough of his "Jesus Mumbo-Jumbo", Peter stole the movie reel for the Passion of the Christ film so that the world would never be exposed to garbage like that again. However, Gibson later hired two priests to kidnap Lois, and he forged a letter to Peter stating that he should return the movie to him at Mount Rushmore, and that he'll get his wife back in return for his cooperation.
Peter arrived at the designated area a minute later, and he gives Gibson the movie reel back. However, he had actually placed a piece of dog dung into the movie case, and Gibson promptly chased after the couple in order to get the real footage back. Gibson is finally defeated when Peter convinces him that the movie reel was in Rushmore's mouth, and he takes the bait and falls off the mountain and to his death.