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Medusa is first seen breaking a dam and turning an insect into stone. Later, she transforms into a pretty woman and saves Holly who lost control of his boat due to the dam's destruction. Medusa then takes Holly to her garden where many statues are inside. Shortly after, Spike arrives and attacks the garden, but Medusa turns him into stone.
Later, Jack, Will and Cha-Ka come to rescue Holly but they are attacked by Medusa's living plants. Finally, they succeed to reach Holly in the garden, however Medusa arrives and attacks them. Holly, Will and Cha-Ka manage to flee away, and Jack uses a mirror to make her looking her own reflection and she turns to stone.