She is a bio-weapon like Jo but with even stronger and more violent tendencies. While Jo is more efficient with guns, Maria relies more on bladed weapons such as swords and cutting wire. In the past, both she and Jo were the remaining fighters in a combat exercise to determine the Syndicate's "Genocide Angel." Maria won by default, but as Jo was only rendered unconscious, Maria never felt like she truly defeated Jo. When Jo is captured by RAPT, Maria disobeys orders and kidnaps Meg to lure Jo into one final battle. She lures Jo onto an aircraft carrier similar to the one where Genocide Angel exercise was held. After a hand-to-hand battle, Jo won and Maria lost her will to fight. She asks Jo what she can do after she gains her humanity; Jo only tells her to live on. She then reunites Jo with Meg only to be surrounded by new RAPT Cybots. She tells Meg to escape with Jo while she fights off the new mechs and appears to have been shot dead.