He presented himself to Iron Man, exclusively hinting that the armored hero was responsible for his existence. After a fight in which M.O.D.O.K. tried to show his superiority to Iron Man, M.O.D.O.K. was defeated and his body exploded.
M.O.D.O.K.'s consciousness was uploaded into yet another form, with minor variations, having fixed the supposed miscalculations that led him to lose his first battle against Iron Man, and tried to destroy the Armored Avenger once more, but failed again and his body was destroyed.
When A.I.M. managed to take over the network of Stark Industries, M.O.D.O.K. presented himself to Iron Man in a third enhanced form. To Iron Man was revealed that M.O.D.O.K. was actually a copy of The Mandarin's consciousness and that he was ready to defeat Iron Man once and for all. Iron Man managed to heavily damage M.O.D.O.K.'s physical form, and when he attempted to survive by uploading his consciousness into the network of Stark Industries, Iron Man willingly sacrificed the network (and, therefore, Stark Industries itself) in order to destroy M.O.D.O.K. for good.