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Born into the tribe of sewer mutants the Morlocks. Not much is known about her time before her first sighting with the X-Men.
Loss was whisked away to "The Hill" where she and her fellow young Morlocks aged at an accelerated rate until they came of age and were known as the Gene Nation. To attest to her fighting prowess she was made a member of Mikhail Rasputin’s personal guard. Her team helped Mikhail in his attack against Storm but she quickly turned the tables and after liberating them from the Darwinist world set them up in an African village so they could live above ground and atone for past sins.
She has remained a mainstay with her team until D'Gard was made leader and they faced hate mongers, she remains with them till now and it is unknown if she lost or retained her powers after M-Day.
A young homeless woman, who retained her mutant abilities after M-Day, emerged living on the streets of New York. She had an uncanny resemblance to Loss, however she looked to be far younger than the mutant who was aged through years of torturous brutality on The Hill. It is possible this young lady was the daughter of Loss. The woman was presumably eaten by Predator X and her boyfriend hired mercenary Fantomex to investigate her disappearance.