Jamie, Karen & Becca are the three main antagonists in the episode "Roasted Guy" and also the main antagonists from Season 13 of Family Guy.

After his roast, Peter befriends these three women, but did not know that his new friends speak ill of him. Then, Peter enlists the help of Lois Griffin for revenge himself. At the end of the episode, Peter returns to his old friends.

Jamie has a daughter called Emily and voiced by Mae Whitman who is honestly defeated by Peter, who had trained, in a diving competition in the pool.

Jamie, Karen & Becca are considered the true main antagonists of Season 13 because Peter Griffin is linked in some way to them during the episode and moreover, they are more present in story than other villains from this season.

They are considerable xenophobes; in fact, they make fun of everyone who is different from them, even a person who has a disability, a problem with the item or is too fat, that person is mocked by them. In fact, although Lois had been kind to them when they first met, the three girls have treacherous mockery for her annoying voice and have wondered how Peter does bear her.

Jamie, with golden blonde hair, is voiced by Rachel MacFarlane.

Karen, the pale blonde hair, is voiced by Alex Borstein.

Becca, with brunette, is voiced by Nicole Sullivan.