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Isabel and Charleen are two young nurses who are employed at the human organ donation center in Arnhem Land in Australia. They are secondary antagonists in the Alex Rider book Snakehead. They are themselves Snakehead agents and are under orders from Winston Yu to guard Alex and make sure he doesn't escape. Isabel comments callously that Alex's blood is worth five thousand pounds a pint, and Charleen cold-bloodledly pretends to be human and welcoming. Even though she is going to be in charge of Alex on the operating table, Charleen still snaps at Jacko & Quombi to take off Alex's irons. Isabel has a room right down from Alex's so he has to be extra quiet when escaping. Their boss Bill Tanner commits suicide on Yu's orders after Alex escapes, and the evil nurses are imprisoned by MI6.