The Man-Beast had kidnapped four members of the Infinity Watch and was holding them unconscious in a stasis tank, in his ship high above the Earth. Man-Beast decided to 'safely' draw power from the Infinity Gems through a computer system of his, rather than directly. He used this "Instrumentality" to avoid becoming intoxicated with the power of the Infinity Gems as Thanos previously had. Warlock came to rescue his captured teammates, and succeeded in defeating the Man-Beast's soldiers and Triax the Terrible. When Warlock confronted the Man-Beast, Man-Beast used his "Instrumentality" to create the Infinity Thrall and sent it to kill Warlock.
This resulted in arguably one of the most impressive cosmic battle-issues of all time, as Warlock tried desperately to stay alive while being hunted by the truly unstoppable and invincible killing machine. Warlock eventually comes up with a plan, luring the mindless Thrall into destroying the Man-Beast ship's engines and generators, depowering the machinery that was creating the Thrall, and destroying half the ship. The Thrall vanishes after destroying its own power source.