Humbaba is an ogre from Sumerian mythology who battled the heroes Gilgamesh and Enkidu in the Epic of Gilgamesh. The brother of the storm demon Pazuzu, he was assigned by the god Enlil to defend the Cedar Forest that served as the home of the gods, and to be a "terror to human beings". His face is described as being that of a lion, but he is commonly depicted in artwork as having a face shaped like human entrails, which the Sumerians used to read omens from the gods. He was also described as being able to breath fire.

In Tablet II of the Epic of Gilgamesh, Gilgamesh and Enkidu set out to the Cedar Forest to slay Humbaba. Forging ahead on his own, Gilgamesh finds the ogre and tricks him into giving up his power by offering his sisters as concubines. Captured by Gilgamesh, Humbaba is taken back to Enkidu, begging for his life. Enkidu convinces his friend to ignore the monster's pleas for mercy, and Humbaba is decapitated by the heroes while attempting to escape.