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|“||Get back here you fucking freaks!, GET BACK HERE YOU FUCKING FREAKS!, YOU DON'T KNOW WHAT YOUR DOING!||„|
|~ Serpo's last words.|
Frank Serpo is the primary antagonist in Dead Island Riptide. It is revealed later on that he was heavily involved in the outbreak on Palanai Island.
Serpo works for an unknown organization, though there are hints of it being a terrorist organization. He was sent to Palanai to record and gather data on the mutations and lethality of Charon's new, mutated strain of the Kuru Virus. He desperately wants the 5 immune survivors for reasons unknown, however, it is most likely for him to use their immunity to mutate the virus even more, possibly into a usable weapon.
When the heroes reach the ADF ship off the shore of Banoi, they meet Frank Serpo on deck, who then orders Charon and Yerema below deck. He is later seen leaving the others to die when the outbreak occurred on the ship. Later when the Heroes contact the military base, Serpo responds claiming he is "sending a chopper to extract the survivors". As the chopper shows up, he orders the immune to board first, but the survivors tell him to take the normal civilians first. Colonel Hardy is then shot and killed for trying to board the chopper first. Logan shoots down the chopper using a LAW missile launcher and the chopper crashes into a nearby fort. Serpo, surviving the crash, kills the pilot to distract the infected so that he can escape. He then waits in the top tower part of the fort, miraculously sustaining no major injuries from the crash.
When the Heroes find a ship to leave, Serpo pleas with them to come with him, but not trusting Serpo, they decide to leave him. He then begins screaming at the Heroes, "Fucking freaks!" and claiming that they don't know what they are doing. In doing so, his yelling attracted nearby infected, which came up behind him and slashed open his neck. He then falls to the ground as the undead consumed him.