I'm the Queen of Corruption, the Mistress of Misdeeds, the Dame of Disaster.
~ Femme Fatale

Femme Fatale is a very conniving supervillainess and a villainess in Cartoon Network's The Powerpuff Girls. She appeared in "Equal Fights", which was also her debut episode and was the main antagonist of that episode. She also had a cameo appearance in the special "Powerpuff Girls Rule!".

She is a bank robber and master thief who cons the Powerpuff Girls into being against males so she can continue to rob banks. She steals only Susan B. Anthony coins since all other current denominations have men on them. She, at the end of the episode "Equal Fights" (also her premiere episode), is promptly beaten up and taken to jail after the Girls tell her who the suffragist Susan B. Anthony was. Unfortunately, after this, she is not ever mentioned or referenced again. It is never stated why Femme hates men; one theory is that she was badly mistreated by her boyfriend/husband, and it caused her great emotional discomfort. Femme Fatale however makes a cameo in The Powerpuff Girls Rule!, which is the series' finale.


Femme Fatale is a very malicious and cruel misandrist who manages to con the Powerpuff Girls to turn against all men. She used her speech to continue her crimes. While she does hate men, she seems to show sheer disrespect to other women despite her lie to the girls and her ultra-female's lib costume, as she stole Susan B. Anthony coins from a female bank president, broke the arm of a policewoman, and copied the hairstyle of a teenage girl. She takes sadistic pleasure in attacking anyone who tries to stop her, both male and female.



  • "Femme fatale" literally means "fatal woman" in French. It's a term used to describe evil beautiful women.
  • Femme Fatale is voiced by Grey DeLisle.
  • The symbols on her outfit and weapon are based on the symbol ♀ for the planet Venus which is named goddess Aphrodite of Greek mythology, and the symbol itself extended into the meaning of the female gender.
  • When she is wearing convict stripes at the end of the episode "Equal Fights", it is revealed that she has blue eyes.
  • Despite making less appearances in the series, she makes a couple more appearances in the book, her role of wanting revenge against the girls since they stopped her.
  • Femme Fatale makes references to two of the major villains: Princess Morbucks (as "that little brat") and Sedusa (as "the chick in the underwear"), as she finds both of them to be ineffective villains because they always end up in jail.
           Powerpuff Girls Villains

Amoeba Boys | Abrakadaver | Boogie Man | Broccoloids | Dick Hardly | Evil Cat | Fake Powerpuff Girls | Femme Fatale | Fuzzy Lumpkins | Gangreen Gang | Gnome | Hacha Chacha | Harold Smith | HIM | K.A.R.R. | Lenny Baxter | Mary Ann Smith | Mike Brikowski | Mr. Mime | Mojo Jojo | Ojo Tango | Patches | Princess Morbucks | Powerpunk Girls | Roach Coach | Rocko Socko | Rolla Ova | Rowdyruff Boys | Sedusa | Sandman | Tonsa Muncha