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I can't very well take over the world until I'm drop-dead gorgeous.
~ Professor Poofenplotz
 
Curse you, Pinky the Chihuahua!!
~ Professor Poofenplotz after being defeated.


Professor Esmeralda Poofenplotz is a recurring antagonist in the Disney animated show, Phineas and Ferb. She is the nemesis of Pinky, Isabella Garcia-Shapiro's pet chihuahua. She was first mentioned in "Day of the Living Gelatin", later appearing in "Isabella and the Temple of Sap" and "Bee Story" as the main antagonist.

She was voiced by recurring guest star Amanda Plummer.

Role

Poofenplotz has been known of her silly attempts of worldwide domination. Her known schemes so far involve replacing handbags, stealing royal jelly, and searching for strong hairspray (her favorite is "Stiff Beauty" hairspray, which originally was only used by clowns). Needless to say, because of her somewhat arrogant personality, Poofenplotz has failed to know about the flaws of her schemes. And because of that, it has allowed Pinky to defeat her in return, leaving an humiliated Poofenplotz to yell out, "Curse you, Pinky the Chihuahua!", similar to how Heinz Doofenshmirtz says whenever his plans get foiled by Perry the Platypus.

Poofenplotz is concerned about her looks, as she can't take over the world until she feels she looks her best. Doofenshmirtz even wrote her a letter in "Bee Story" where he informed her that her application into membership in L.O.V.E.M.U.F.F.I.N. had been declined due to her schemes being deemed not close to their standards.

           Phineas and Ferb Villains

Doofenshmirtz Evil Incorporated
Heinz Doofenshmirtz | Vanessa Doofenshmirtz | Norm | Gelatin Monster | Doofenshmirtz's Mecha | Rodrigo | Mindless Repulsive Pharmacists

L.O.V.E.M.U.F.F.I.N.
Aloyse Von Roddenstein | Dr. Bloodpudding | Dr. Diminutive | Orville Von Roddenstein | Professor Bannister | Bannister's Thugs | Me-Positive & Me-Negative | Dr. Killbot | Warehouse Goons

Doofenshmirtz Family (2nd Dimension)
Heinz Doofenshmirtz (2nd Dimension) | Charlene Doofenshmirtz (2nd Dimension) | Vanessa Doofenshmirtz (2nd Dimension) | Norm-Bots | Goozim | Animal-Borgs (Perry the Platyborg, Peter the Pandaborg & Pinky the Chihuahuaborg) | Tony Marzulo

Other Evil Scientists
Professor Destructicon | Dr. Gevaarlijk | Mitch | The Regurgitator | Esmeralda Poofenplotz | Khaka Peü Peü | Evil Carl (Evil Flynn-Fletcher Robots) | Mittington Random (The Klimpalooners) | Professor Mystery | Professor Parenthesis (Mecha-Fleas)

Time Shift
Jekyll Doofenshmirtz | Doofengung | Doofus Khan | Doofenshmirtz (1914) | Corn Colossus of Juatchadoon | Norm (1914) | Professor Von Doofenshmirtz | Pneumatic Pnorman | Darthenshmirtz | Darth Ferb | Candace's C.O. | Norm-3PO | Stormtrooper Candace | Stormtrooper Baljeet | Stormtrooper Buford

Fictional Characters
Control Freak | Smile Away Reformatory School Sergeant | Giant Buford | Malifishmertz | Meatlings | Lawn Gnorme | Keeper of the Bridge of Comprehension | Candace's Id | Worthington Dubois | Professor Nibbles | Der Kinderlumper

Misc.
Brobots | Suzy Johnson | Dennis the Rabbit | Busting Candace | Potato Gremlins | Liam McCracken | Morg | Peggy McGee