As goddess of war, Enyo is responsible for orchestrating the destruction of cities, often accompanying Ares into battle, and depicted "as supreme in war". During the Trojan War which befell the legendary city of Troy, Enyo inflicted horror and bloodshed in the war, along with Eris, and Phobos ("Fear") and Deimos ("Dread"), the two sons of Ares. She, Eris, and the two sons of Ares are depicted on Achilles’s shield.
Enyo was involved in the war of the Seven Against Thebes and Dionysus’s war with the Indians as well. Enyo so delighted in warfare that she even refused to take sides in the battle between Zeus and the monster Typhon:
- "Eris (Strife) was Typhon's escort in the mellay, Nike (Victory) led Zeus into battle . . . impartial Enyo held equal balance between the two sides, between Zeus and Typhon, while the thunderbolts with booming shots revel like dancers in the sky."
At Thebes and Orchomenos, a festival called Homolôïa, which was celebrated in honour of Zeus, Demeter, Athena and Enyo, was said to have received the surname of Homoloïus from Homoloïs, a priestess of Enyo. A statue of Enyo, made by the sons of Praxiteles, stood in the temple of Ares at Athens. Among the Graeae in Hesiod there is one called Enyo.
Enyo also had an identity with one of the Graeae, three sisters who shared one eye and one tooth among them, along with Deino ("Dread") and Pemphredo ("Alarm").