Elijah Creem is the main antagonist in the 20th Alex Cross novel Alex Cross, Run. He is a plastic surgeon whose life was ruined by Alex Cross, and he is now out on revenge.

Creem is a plastic surgeon who illegally distributes drugs and has sex with underage girls (while making porn videos) when Cross finds this out, he is arrested. But Creem breaks out of jail and gives himself an entirely new face, and wants revenge of Alex Cross.