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Dr Marek was a minor villain mentioned in the horror game Phantasmagoria 2: A Puzzle of Flesh, an infamous "interactive movie" video-game that had elements of both psychological and body-horror as well as a mentally unstable protagonist and many minor villains (or at the least, negative role models) throughout the often complicated storyline.

Dr Marek was a corrupt official at a psychiatric hospital (more accurately an asylum as their methods were extremely cruel, such as lobotomy and shock therapy (practices now considered inhumane - even torture) ) - working with the megalomaniac known as Paul Allen Warner he supplied "Project Threshold" with many test subjects from his own patients.