Dr. Machino is the titular villain and final boss from Awesome Possum Kicks Dr. Machino's Butt. Seeking to take over the world, he sends an army of robots which destroys the environment, so the Awesome Possum goes after him to teach him a lesson, fighting his robots and penetrating his Domain, Fortress of Garbage.
Dr. Machino fights in a robotic suit, but much like every other enemy in the game he just walks back and forth and launches his attacks every now and then, which include guided missiles and a spring glove. After being defeated his suit explodes and the Awesome Possum finally kicks his butt.
- Dr. Machino is a pun on the word "machine".