Comrade Red is Major Glory's arch nemesis on Dexter's Laboratory. Like Major Glory represents the USA, Comrade Red represents the Soviet Union with their relationship being a parody of the conflicts that occurred during the Cold War between the Soviet Union and the USA. Major Glory represents most aspects of the Western World such as democracy, the free world and heroism. Comrade Red represents communism and the Soviet Union, and also believes that the world should be crushed. He dresses in Russian attire and like Major Glory (who decorates his costume like his country's flag) he decorates his costumes with the designs of the former Russian flag of the Soviet Union used prior to 1991. He also uses a hammer and sickle as weapons.
As Major Glory is a parody of Captain America, Comrade Red is a parody of Red Skull.
He made a cameo appearance in The Powerpuff Girls episode "Members Only", as one of the members of the Association of World Super Men.