Cleopatra is the final boss from Double Dragon 3: The Rosetta Stone. She is found in the inner chamber of her pyramid, where she guards her secret treasure from beyond her grave. In her first form she appears as a mummy, and after being defeated her spirit raises from her dead body and warps everyone to another dimension for the final fight. She constantly teleports around the room, attacking with various projectiles and telekinetically pushing the player. Upon being defeated her spirit vanishes and her treasure is revealed.

In the NES version of the game, her name is changed to Princess Noiram and instead of being Cleopatra she is revealed as actually being Marian, who had been possessed by an evil spirit.