| "Cerberus" may be referring to two or more different villains. If you're uncertain which one you're looking for, just flip a coin.|
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- Cerberus (mythology) - Guardian of the underworld in Greek mythology.
- Cerberus (Dante's Inferno) - Boss in the videogame Dante's Inferno.
- Cerberus (Devil May Cry) - Boss in Devil May Cry 3.
- Cerberus (Disney Hercules) - gigantic three-headed dog and servant of Hades.
- Cerberus (God of War) - enemy-type in the videogame God of War.
- Cerberus (Manhunt) - A group of soldiers hired by Lionel Starkweather to protect him and villains in Manhunt.
- Cerberus (Marvel) - Supervillain based on the Greek myth
- Cerberus (Mass Effect) - A pro-human extremist group in the Mass Effect universe, controlled by the Illusive Man.
- Cerberus (Resident Evil) - enemies in the Resident Evil series, zombies posing as dogs.
- Cerberumon- A three-headed Dog Digimon that was a villain in Digimon Frontier, and Digimon Xros Wars, and a possible villain in Digimon Data Squad
- Mole Cerberus - Boss in God of War II.