Paranoid Villains are very common antagonists who are fueled by a deep fear of being harmed or weakened by others/someone and therefore, it is hard for them to trust others. This type of evildoer is very common in mythology, embodied in individuals like Cronus and Herod, who are willing to commit terrible atrocities to try and prevent what they see as an impending doom (they almost always fail).

Basically, a villain who lives in fear of being defeated by a particular hero, prophecy or, in some cases, even another villain and utilizes extreme methods to try and prevent their own doom (ironically often causing said doom) can be added to this category.