Villains in Japanese animation with expressive features and symbolism not always found in other forms of animation. Anime characters (either heroes or villains) are depicted with traits more realistic and/or less cartoonish, especially when compared to Western media. This often overlaps with Manga Villains due to manga being adapted into anime and vice versa.
IMPORTANT: Do NOT add Villains from Western animation, as they belong in Cartoon Villains, regardless of whether or not they were anime-inspired or anime-esque, though they might be considered characters from anime imitations (i.e. The Boondocks, Avatar: The Last Airbender, The Legend of Korra, RWBY, Ōban Star-Racers).
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- Yakon
- Yakumo Oomori
- Yaldabaoth (Persona)
- Yama (Yozakura Family)
- Yamainu
- Yamazin Toka
- Yamcha
- Yami (History's Strongest Disciple Kenichi)
- Yami Bakura
- Yami Marik
- Yamikage
- Yammy Llargo
- Yamu
- Yana
- Yang Xiu
- Yanmamon
- Yanni Yogi
- Yard
- Yasha
- Yasha (Sailor Moon)
- Yasunori Kato
- Yasuyuki Ootsuka
- Yayoi Kuribayashi
- Yazan Gable
- Yeagerists
- Yelena (Attack on Titan)
- Yellow Radio
- Yellow Scarves (Durarara)
- Yellow Turbans
- Yellow Zelkova
- Yetti
- Yggdmillenia Clan
- Yhwach
- Yin-jiao & Jin-jiao
- Ying Ranma
- Ymir Fritz
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- Yodai Higashizawa
- Yoki (Fullmetal Alchemist)
- Yoko Kurama
- Yoma Hashimoto
- Yomi
- Yomi (History's Strongest Disciple Kenichi)
- Yomi (Sekirei)
- Yomi Isayama
- Yomotsu Hirasaka
- Yoshie Kurahashi
- Yoshihiro Kira
- Yoshihisa Kira
- Yoshikage Kira
- Yoshikazu
- Yoshimitsu Kaidou
- Yoshio Kanzaki
- Yoshitaka Nakabayashi
- Yoshiuo Minamoto
- Youma (Sailor Moon)
- Youma (The Twelve Kingdoms)
- Younger Toguro
- Ypsilon
- Yu Hojo
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- Yuan (Shenmue)
- Yuan Shao (Romance of the Three Kingdoms)
- Yuan Shao's Army
- Yuan Shu (Romance of the Three Kingdoms)
- Yuan Tao
- Yubaba
- Yubel
- Yuda
- Yuebing
- Yugi (Tenchi in Tokyo)
- Yugo Tennouji
- Yui Hongo
- Yuichirou Kanzaki
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- Yuji Sakai
- Yujiro Hanma
- Yuka Suzuki
- Yukako Yamagishi
- Yukari Yakumo
- Yuki (Kingdom)
- Yukinori Shinohara
- Yukio Hans Vorarlberna
- Yukio Oikawa
- Yukishiro Enishi
- Yukiteru Amano
- Yukitoshi Shimizu
- Yukitsu Kusuda
- Yukiya Naruse
- Yula
- Yume Hasegawa
- Yumemi Yumemite
- Yumeno Kyusaku
- Yumi Horikoshi
- Yumie Takagi
- Yun Sanho
- Yuni
- Yuno Gasai
- Yura
- Yura the Great
- Yuri (Mermaid Melody)
- Yuri (Yu-Gi-Oh! ARC-V)
- Yuri Briar
- Yuri Kellerne
- Yuri Nakamura
- Yurika Hakonaka
- Yurine Hanazono
- Yuta and Kodama Melone
- Yuto Ijika
- Yuu
- Yuu Ren
- Yuuichi Katagiri
- Yuuji Kazami Clone
- Yuuka Kazami
- Yuuki Kagurazaka
- Yuuki Terumi
- Yuuna Kōbe
- Yuuya Kizami
- Yuya Fungami
- Yuyuko Saigyouji
- Yveltal
- Yylfordt Granz
- Yzak Joule
- Yūichirō's Parents
- Yūjin Ōzora
- Z (Tenchi Mayo!)
- Z-ARC
- Z-Master
- Z-one
- Zabi Family
- Zabine Chareux
- Zaboera
- Zabuza Momochi
- Zadam
- Zadkiel (Date A Live)
- Zafkiel
- ZAFT
- Zagi
- Zagred
- Zakenna
- Zaku Abumi
- Zakuro
- Zamasu
- Zamza
- Zanark
- Zanark Avalonic
- Zancrow
- Zane Truesdale
- Zangetsu
- Zangief
- Zangya
- Zank
- Zannin
- Zanscare Empire
- Zarbon
- Zaria
- Zash Caine
- Zatola
- Zattan
- Zazan
- Zebra (Fist of the North Star)
- Zebra (Toriko)
- Zechs Merquise
- Zeed (Fist of the North Star)
- ZeedMillenniummon
- Zeke Yeager
- Zekrom (Pokémon)
- Zelas Metallium
- Zeldris
- Zelos (Saint Seiya)
- Zen-Oh
- Zenet Surrow
- Zenin Family
- Zennon (Devilman 1972)
- Zennon (Devilman)
- Zeno (Zatch Bell!)
- Zenon Zogratis
- Zentradi
- Zeo (One Piece)
- Zeo Zagart
- Zepes Indu
- Zephyr (One Piece)
- Zephyr (Ragnarok)
- Zerbebuth
- Zeref Dragneel
- Zero (Loveless)
- Zero (Pokémon)
- Zero (Tenchi Muyo!)
- Zero (Yashahime: Princess Half-Demon)
- Zero Numbers
- Zero Tails
- Zero.EXE
- Zerofuku (Record of Ragnarok)
- Zeruel
- Zeus (Record of Ragnarok)
- Zhang Liao (Romance of the Three Kingdoms)
- Zhong Dynasty
- Zhu Jin