Carlos Santana is the main antagonist of the 2007 spoof/comedy movie Delta Farce. He is a Mexican warlord who terrorizes the peaceful village of La Miranda, and he is not to be confused with the real-life singer of the same name.

He was portrayed by Danny Trejo.

When three bumbling American soldiers are accidentally deployed in Mexico, they defend La Miranda from Santana and his bandits, thinking they're in Iraq. In the end, the 101st Airborne Division arrives to back them up and imprisons the outlaws, and Larry, Bill, and Everett receive Silver Stars.