The Brood Imperiatrix (also known as the Great Mother) is an abnormally large and powerful Brood Queen from Marvel comics and a recurring enemy of the X-Men and other heroes of the Marvel Universe.

Like all Brood Queens she seeks to spread her influence across time and space, via infecting other races and like most of her kind was not (at least initially) a malevolent being but rather an amoral parasite who cared for her "young" and reproduced the only way she knew how.