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Bosco is the main antagonist in the 2010 film, Marmaduke. He is voiced by Kiefer Sutherland.

He is a Beauceron. He gets jealous of the other male dogs in the gang, including its newest comer. He is controlling and violent. He is also Jezebel's boyfriend. At the end of the movie, everyone turns on Bosco, who leaves, vowing revenge, however only to be scared away by a bee on his nose.